LOCUS       XM_045915               1896 bp    mRNA    linear   PRI 13-MAY-2002
DEFINITION  Homo sapiens transcription factor 1, hepatic; LF-B1, hepatic
            nuclear factor (HNF1), albumin proximal factor (TCF1), mRNA.
ACCESSION   XM_045915
VERSION     XM_045915.4  GI:20550915
KEYWORDS    .
SOURCE      human.
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1896)
  AUTHORS   NCBI Annotation Project.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-MAY-2002) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
COMMENT     GENOME ANNOTATION REFSEQ:  This model reference sequence was
            predicted from NCBI contig NT_028327 by automated computational
            analysis using gene prediction method: BLAST, supported by mRNA
            evidence.
            Also see:
                Documentation of NCBI's Annotation Process
                
            On May 13, 2002 this sequence version replaced gi:20506002.
FEATURES             Location/Qualifiers
     source          1..1896
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="12"
     gene            1..1896
                     /gene="TCF1"
                     /note="HNF1; LFB1; HNF1A; MODY3"
                     /db_xref="LocusID:6927"
                     /db_xref="MIM:142410"
     CDS             1..1896
                     /gene="TCF1"
                     /codon_start=1
                     /product="transcription factor 1, hepatic; LF-B1, hepatic
                     nuclear factor (HNF1), albumin proximal factor"
                     /protein_id="XP_045915.4"
                     /db_xref="GI:20550916"
                     /db_xref="LocusID:6927"
                     /db_xref="MIM:142410"
                     /translation="MVSKLSQLQTELLAALLESGLSKEALLQALGEPGPYLLAGEGPL
                     DKGESCGGGRGELAELPNGLGETRGSEDETDDDGEDFTPPILKELENLSPEEAAHQKA
                     VVETLLQEDPWRVAKMVKSYLQQHNIPQREVVDTTGLNQSHLSQHLNKGTPMKTQKRA
                     ALYTWYVRKQREVAQQFTHAGQGGLIEEPTGDELPTKKGRRNRFKWGPASQQILFQAY
                     ERQKNPSKEERETLVEECNRAECIQRGVSPSQAQGLGSNLVTEVRVYNWFANRRKEEA
                     FRHKLAMDTYSGPPPGPGPGPALPAHSSPGLPPPALSPSKVHGVRYGQPATSETAEVP
                     SSSGGPLVTVSTPLHQVSPTGLEPSHSLLSTEAKLVSAAGGPLPPVSTLTALHSLEQT
                     SPGLNQQPQNLIMASLPGVMTIGPGEPASLGPTFTNTGASTLVIGLASTQAQSVPVIN
                     SMGSSLTTLQPVQFSQPLHPSYQQPLMPPVQSHVTQSPFMATMAQLQSPHALYSHKPE
                     VAQYTHTGLLPQTMLITDTTNLSALASLTPTKQVFTSDTEASSESGLHTPASQATTLH
                     VPSQDPASIQHLQPAHRLSASPTVSSSSLVLYQSSDSSNGQSHLLPSNHSVIETFIST
                     QMASSSQ"
     misc_feature    598..840
                     /gene="TCF1"
                     /note="HOX; Region: Homeodomain"
                     /db_xref="CDD:smart00389"
     misc_feature    598..816
                     /gene="TCF1"
                     /note="homeobox; Region: Homeobox domain"
                     /db_xref="CDD:pfam00046"
BASE COUNT      402 a    684 c    536 g    274 t
ORIGIN      
        1 atggtttcta aactgagcca gctgcagacg gagctcctgg cggccctgct ggagtcaggg
       61 ctgagcaaag aggcactgct ccaggcactg ggtgagccgg ggccctacct cctggctgga
      121 gaaggccccc tggacaaggg ggagtcctgc ggcggcggtc gaggggagct ggctgagctg
      181 cccaatgggc tgggggagac tcggggctcc gaggacgaga cggacgacga tggggaagac
      241 ttcacgccac ccatcctcaa agagctggag aacctcagcc ctgaggaggc ggcccaccag
      301 aaagccgtgg tggagaccct tctgcaggag gacccgtggc gtgtggcgaa gatggtcaag
      361 tcctacctgc agcagcacaa catcccacag cgggaggtgg tcgataccac tggcctcaac
      421 cagtcccacc tgtcccaaca cctcaacaag ggcactccca tgaagacgca gaagcgggcc
      481 gccctgtaca cctggtacgt ccgcaagcag cgagaggtgg cgcagcagtt cacccatgca
      541 gggcagggag ggctgattga agagcccaca ggtgatgagc taccaaccaa gaaggggcgg
      601 aggaaccgtt tcaagtgggg cccagcatcc cagcagatcc tgttccaggc ctatgagagg
      661 cagaagaacc ctagcaagga ggagcgagag acgctagtgg aggagtgcaa tagggcggaa
      721 tgcatccaga gaggggtgtc cccatcacag gcacaggggc tgggctccaa cctcgtcacg
      781 gaggtgcgtg tctacaactg gtttgccaac cggcgcaaag aagaagcctt ccggcacaag
      841 ctggccatgg acacgtacag cgggcccccc ccagggccag gcccgggacc tgcgctgccc
      901 gctcacagct cccctggcct gcctccacct gccctctccc ccagtaaggt ccacggtgtg
      961 cgctatggac agcctgcgac cagtgagact gcagaagtac cctcaagcag cggcggtccc
     1021 ttagtgacag tgtctacacc cctccaccaa gtgtccccca cgggcctgga gcccagccac
     1081 agcctgctga gtacagaagc caagctggtc tcagcagctg ggggccccct cccccctgtc
     1141 agcaccctga cagcactgca cagcttggag cagacatccc caggcctcaa ccagcagccc
     1201 cagaacctca tcatggcctc acttcctggg gtcatgacca tcgggcctgg tgagcctgcc
     1261 tccctgggtc ctacgttcac caacacaggt gcctccaccc tggtcatcgg cctggcctcc
     1321 acgcaggcac agagtgtgcc ggtcatcaac agcatgggca gcagcctgac caccctgcag
     1381 cccgtccagt tctcccagcc gctgcacccc tcctaccagc agccgctcat gccacctgtg
     1441 cagagccatg tgacccagag ccccttcatg gccaccatgg ctcagctgca gagcccccac
     1501 gccctctaca gccacaagcc cgaggtggcc cagtacaccc acacgggcct gctcccgcag
     1561 actatgctca tcaccgacac caccaacctg agcgccctgg ccagcctcac gcccaccaag
     1621 caggtcttca cctcagacac tgaggcctcc agtgagtccg ggcttcacac gccggcatct
     1681 caggccacca ccctccacgt ccccagccag gaccctgcca gcatccagca cctgcagccg
     1741 gcccaccggc tcagcgccag ccccacagtg tcctccagca gcctggtgct gtaccagagc
     1801 tcagactcca gcaatggcca gagccacctg ctgccatcca accacagcgt catcgagacc
     1861 ttcatctcca cccagatggc ctcttcctcc cagtaa
//
